Hatice Neval ert rk
Neval Ertürk is an award-winning teacher and scholar. In recognition of her teaching and research with the undergraduate students at Converse, she received the South Carolina Independent Colleges and Universities (SCICU) Teaching in Excellence Award in 2008. In 2012 she was recognized with the 学术 and Creative Achievement Award by Converse for “being at the forefront of mentoring student research” as well as her STEM Outreach activities to the local high school students many of which led to national awards for the students. She was also a recipient of the 2012 Student 服务: Above and Beyond Award for her service to students.
在万博地址，. Ertürk teaches a wide variety of courses in biology including Genetics, 细胞生物学, 研究 Methods in Biology, Molecular Biology of the Cell, 法医遗传学, Science and Gender and introductory biology courses. She believes research complements teaching, thus she regularly works with students on original research. She also is a keen advocate of promoting science among high school students and professional development assistant to STEM Workforce.
When not teaching or researching, she spends her time traveling, 阅读, watching science fiction movies and exploring nature.
简历
阅读更多关于Dr. Ertürk’s activities and accomplishments:
学术 & 研究活动
Dr. Ertürk is an active participant of inter-institutional research initiatives in South Carolina. She serves as the Chair of the Student Awards Committee of the South Carolina Upstate 研究 Symposium, Review Board of SCICU Faculty Sponsored 研究 Program, and Science Review Committee of Piedmont III Region Science Fair. In 2013, she was elected to serve a three-year term on the Advisory Board of Intel International Science and Engineering Fair. She received a Plaque of Recognition from the South Carolina Upstate 研究 Symposium for supporting the research and scholarly efforts of faculty and students in the Upstate in 2012 and a Certificate of Recognition from the South Carolina Academy of Science for her excellence in the support and development of talent and research in the State of South Carolina in 2011. She was also nominated to The Governor’s Award for Excellence in Science Outreach in 2010.
An active scholar, Dr. Ertürk’s research projects with her students and STEM workforce received numerous grants from various agencies and awards at the national and regional levels. She has professional memberships in American Association for the Advancement of Science (AAAS), American Society for Plant Biologist (ASPB), Association of Southeastern Biologists (ASB), Council of 本科 研究ers (CUR), Association for Women in Science (AWIS), Association of College and University Biology Educators (ACUBE), 导师净, and Earthwatch Institute.
出版物 & 演讲
- Alscher R. G.埃尔特克，N. 希思，L。. S. (2002). Antioxidants and Reactive Oxygen Species in Plants: Role of superoxide dismutases (SODs) in controlling oxidative stress in plants. Journal of Experimental Botany, 53(372), 1331-1341.
- Erturk H.N. 和Esen, A. (1995). A b-glucosidase aggregating factor (BGAF) is present in “null” genotypes of maize. Maize Genetics Newsletters,69:25-26.
- Erturk H.N. 和Unlu H. (1991). The phenotypic abnormalities caused by an organophosphorus insecticide, Dichlorvos (DDVP), in Drosophila melanogaster. Doga-Tr. 动物学杂志, 15:76-83.
- Erturk H.N. 和Unlu H. (1991). The effects of dichlorvos (DDVP), on crossing-over in Drosophila melanogaster. Doga-Tr. 生物学杂志， 15:139-143.
- Unlu H. 埃尔图克，H.N. (1991). The effects of dichlorvos (DDVP), on sex-ratio in Drosophila melanogaster. Doga-Tr. 动物学杂志, 15:177-184.
INBRE文摘
Investigation of Aryl Hydrocarbon Receptor Antagonistic Effects of 灵芝
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. It regulates the responses of the cell to a variety of polyaromatic hydrocarbons (PAH). AhR mediated toxicity to these chemicals is associated with a variety of pathological conditions, 包括癌症. Therefore AhR modulation currently is studied as an important physiological process. Reishi (灵芝), cordyseps (Cordyceps sinensis) and hawthorn (Crataegus pinnatifida) are commonly used in Chinese medicine to treat diseases such as diabetes, 高血压, and cancer as well as strengthening immune system. Previously an association herb produced by using these three supplements was reported as an AhR antagonist causing reduction in Cyp1A1 projection in cells treated with TCDD. The purpose of this research is to show identify the supplement that acts as an AhR antagonist. Real-time RT-PCR will be used to measure CYP1A1 gene expression in MCF-7 cells treated with the supplements and 2,3,7,8-Tetrachlorodibenzodioxin (TCDD).
Investigation of cancer-selective apoptotic effects of 灵芝
Interest in using herbal medicines as an alternative to conventional treatments has been present for hundreds of years. 灵芝, commonly known as reishi, is a mushroom extract used as a traditional herbal treatment for a variety of symptoms and illnesses. Deemed “the mushroom of immortality” in China, it has been reported to help circulation and blood pressure, assist in regulation of the immune system, 最值得注意的是, suppress cancerous tumors. (1) It is believed to be an effective as a complementary and alternative medicine (CAM) in cancerous growth, especially when used in conjunction with other types of conventional treatment. Reishi is currently known to cause apoptosis in cancer cells, but the mechanisms by which the apoptosis occur has not been identified. The primary mechanism of apoptosis is caspase dependent. 还存在, or cysteine-aspartic proteases, are a group of protease enzymes which play a major role in the controlled destruction of cellular parts during programmed cell death. Caspase dependent apoptosis can be triggered by either intrinsic or by extrinsic mechanisms. The intrinsic mechanism is modulated by Caspase-8 and the extrinsic mechanism is modulated by Caspase-9 enzyme (2). The purpose of this study is to examine the type of mechanism in which 灵芝 triggers apoptosis in cancerous cells, and if it also triggers apoptosis in noncancerous cells as well. It is important to know whether apoptosis is caused by an intrinsic or extrinsic mechanism, because knowing which pathway causes the apoptotic effect 给s us a greater understanding of how and why reishi targets cancer cells specifically and can be helpful in identifying reishi’s pharmaceutical potential.
Genetoxicity Preventative Effects of 灵芝 (reishi), Cordyceps sinensis (Cordyceps) andCrataegus monogyna (hawthorn) in Rats
Medicinal practices such as Ayurveda and Traditional Chinese Medicine (TCM) use phytoproduct mixtures, 称为关联, in order to maximize the therapeutic benefits of these supplements. A commercially available association as well as its individual compounds 灵芝 (reishi), Cordyceps sinensis(Cs) and Crataegus oxiacantha (hawthorn) are used in traditional medicine for their health benefits such as antitumor and immuno-modulatory effects. In this study genotoxicity causing and genotoxicity preventive capacity of this association as well as individual supplements were tested by using rat bone marrow micronucleus test. For each experimental group five animals were used. A total of 2,000 polychromatic erythrocytes (PCE) were scored per animal. Data was analyzed by using a t-test. A significant decrease in the number of micronucleated cells was observed in the group that received the association and the individual supplements in combination with a genotoxic agent (p < .05), suggesting that individual supplements have a preventative effect on genotoxic agent induced genotoxicity. 然而, a slight increase in the formation of micronucleus in the groups that received reishi and cordyceps group also observed. Further studies to determine potential toxicity is recommended.